Product Overview
Icotinib Hydrochloride | T2307 | TargetMol Chemicals
CAS: 1204313-51-8
Smiles: Cl.C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1
Formula: C22H22ClN3O4
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR
Receptor: N/A
Bioactivity: Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.
Molecular Weight: 427, 89
