Product Overview
IDE1 | T3162 | TargetMol Chemicals
CAS: 1160927-48-9
Smiles: OC(=O)CCCCCC(=O)N\N=C\c1ccccc1C(O)=O
Formula: C15H18N2O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-β signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.
Molecular Weight: 306, 318