Product Overview
iMDK | T9460 | TargetMol Chemicals
CAS: 881970-80-5
Smiles: Fc1ccc(Cc2cn3cc(nc3s2)-c2cc3ccccc3oc2=O)cc1
Formula: C21H13FN2O2S
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K
Receptor: N/A
Bioactivity: iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors without harming normal cells and mice.
Molecular Weight: 376, 41