Product Overview
Inauhzin | T1887 | TargetMol Chemicals
CAS: 309271-94-1
Smiles: CCC(Sc1nnc2c(n1)[nH]c1ccccc21)C(=O)N1c2ccccc2Sc2ccccc12
Formula: C25H19N5OS2
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: Sirtuin
Receptor: N/A
Bioactivity: Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
Molecular Weight: 469, 58
