Product Overview
Indophagolin | T8946 | TargetMol Chemicals
CAS: 1207660-00-1
Smiles: FC(F)(F)c1cc(NS(=O)(=O)c2cc3N(CCc3cc2Br)C(=O)C2CC2)ccc1Cl
Formula: C19H15BrClF3N2O3S
Pathway: Autophagy|||GPCR/G Protein|||Membrane transporter/Ion channel|||Neuroscience
Target: P2X Receptor|||5-HT Receptor|||P2 Receptor|||Autophagy
Receptor: N/A
Bioactivity: Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.
Molecular Weight: 523, 75