Product Overview
Indoximod | T6543 | TargetMol Chemicals
CAS: 110117-83-4
Smiles: Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
Formula: C12H14N2O2
Pathway: Metabolism
Target: Indoleamine 2, 3-Dioxygenase (IDO)
Receptor: N/A
Bioactivity: Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
Molecular Weight: 218, 256
