Product Overview
Infigratinib | T1975 | TargetMol Chemicals
CAS: 872511-34-7
Smiles: CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1
Formula: C26H31Cl2N7O3
Pathway: Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||FGFR
Receptor: N/A
Bioactivity: Infigratinib (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
Molecular Weight: 560, 48
