Product Overview
Ipatasertib HCl | T27621 | TargetMol Chemicals
CAS: 1489263-16-2
Smiles: Cl.CC(C)NC[C@@H](C(=O)N1CCN(CC1)c1ncnc2[C@H](O)C[C@@H](C)c12)c1ccc(Cl)cc1
Formula: C24H33Cl2N5O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ipatasertib is an orally active, potent and selective Akt inhibitor with antitumor activity. Inhibition of Akt activity by Ipatasertib resulted in blockade of cell-cycle progression and reduced viability of cancer cell lines. Markers of Akt activation, including high-basal phospho-Akt levels, PTEN loss, and PIK3CA kinase domain mutations, correlate with sensitivity to Ipatasertib.
Molecular Weight: 494, 46
