Product Overview
IQ 1 | T3635 | TargetMol Chemicals
CAS: 331001-62-8
Smiles: CC(=O)c1ccc(N\N=C(\C(N)=O)C2=NC(C)(C)Cc3ccccc23)cc1
Formula: C21H22N4O2
Pathway: Cytoskeletal Signaling|||Stem Cells
Target: Wnt/beta-catenin
Receptor: N/A
Bioactivity: Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4 and Sox2 transcription factors. Binds to serine/threonine phosphatase PP2A and prevents PP2A/Nkd interaction.
Molecular Weight: 362, 433
