Product Overview
IQ-1S free acid | T3627 | TargetMol Chemicals
CAS: 23146-22-7
Smiles: O\N=C1/c2ccccc2-c2nc3ccccc3nc12
Formula: C15H9N3O
Pathway: MAPK|||NF-Κb
Target: NF-κB|||JNK
Receptor: N/A
Bioactivity: IQ-1S is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
Molecular Weight: 247, 257
