Product Overview
Irisflorentin | T6S1665 | TargetMol Chemicals
CAS: 41743-73-1
Smiles: COc1cc(cc(OC)c1OC)-c1coc2cc3OCOc3c(OC)c2c1=O
Formula: C20H18O8
Pathway: Immunology/Inflammation|||Others
Target: Others|||NO Synthase
Receptor: N/A
Bioactivity: 1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
Molecular Weight: 386, 356
