Product Overview
IRL 2500 | T15596 | TargetMol Chemicals
CAS: 169545-27-1
Smiles: CN([C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1
Formula: C36H35N3O4
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: IRL 2500 is an effective antagonist of the Endothelin receptor. IRL 2500 suppresses ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo. IRL 2500 displays (IC50:1.3 and 94 nM for ETB and ETA receptors, respectively).
Molecular Weight: 573, 693
