Product Overview
Isocryptotanshinone | TN1775 | TargetMol Chemicals
CAS: 22550-15-8
Smiles: C[C@@H]1COC2=C1C(=O)c1ccc3c(CCCC3(C)C)c1C2=O
Formula: C19H20O3
Pathway: JAK/STAT signaling|||MAPK|||Stem Cells
Target: ERK|||JNK|||STAT
Receptor: N/A
Bioactivity: Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
Molecular Weight: 296, 366