Product Overview
Isodiospyrin | TN4283 | TargetMol Chemicals
CAS: 20175-84-2
Smiles: Cc1cc(O)c2C(=O)C=CC(=O)c2c1-c1c(C)cc2C(=O)C=CC(=O)c2c1O
Formula: C22H14O6
Pathway: DNA Damage/DNA Repair|||Microbiology/Virology
Target: Topoisomerase|||Antifection
Receptor: N/A
Bioactivity: Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the minimum inhibitory concentrations (MICs) against Gram-positive bacteria ranged from 0.78 to 50 microg/mL; it shows high antifungal activity against P. obscurans at 30uM with 81.4% growth inhibition, and moderate activity against P. viticola (36.6%).
Molecular Weight: 374, 4