Isofraxidin | T5S0045

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€168.00 - €219.00
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TMC-T5S0045
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Product Overview

Isofraxidin | T5S0045 | TargetMol Chemicals

CAS: 486-21-5

Smiles: COc1cc2ccc(=O)oc2c(OC)c1O

Formula: C11H10O5

Pathway: Immunology/Inflammation|||MAPK|||Neuroscience|||Proteases/Proteasome

Target: MMP|||ERK|||p38 MAPK|||TLR|||COX

Receptor: N/A

Bioactivity: 1. Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. 3. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.

Molecular Weight: 222, 196

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