Product Overview
Isojacareubin | TN4300 | TargetMol Chemicals
CAS: 50597-93-8
Smiles: CC1(C)Oc2cc(O)c3c(oc4c(O)c(O)ccc4c3=O)c2C=C1
Formula: C18H14O6
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling|||MAPK|||Microbiology/Virology
Target: MAPK|||PKC|||Antifection
Receptor: N/A
Bioactivity: Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of protein kinase C (PKC), suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo, thus, it as a promising lead compound for the development of new antihepatoma agents.
Molecular Weight: 326, 31