Product Overview
Isoliquiritin apioside | T3860 | TargetMol Chemicals
CAS: 120926-46-7
Smiles: OC[C@H]1O[C@@H](Oc2ccc(\C=C\C(=O)c3ccc(O)cc3O)cc2)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@@H](O)[C@@H]1O
Formula: C26H30O13
Pathway: MAPK|||NF-Κb|||Proteases/Proteasome
Target: MMP|||p38 MAPK|||NF-κB
Receptor: N/A
Bioactivity: Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity.
Molecular Weight: 550, 513
