Product Overview
Isotaxiresinol | TN4334 | TargetMol Chemicals
CAS: 26194-57-0
Smiles: COc1cc2C[C@@H](CO)[C@H](CO)[C@@H](c3ccc(O)c(O)c3)c2cc1O
Formula: C19H22O6
Pathway: Apoptosis
Target: TNF
Receptor: N/A
Bioactivity: Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. Isotaxiresinol may be useful for treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency.
Molecular Weight: 346, 38