Product Overview
Isotetrandrine | TN1806 | TargetMol Chemicals
CAS: 477-57-6
Smiles: COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34
Formula: C38H42N2O6
Pathway: Immunology/Inflammation|||MAPK|||NF-Κb
Target: IL Receptor|||NF-κB|||MAPK
Receptor: N/A
Bioactivity: Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process.
Molecular Weight: 622, 762
