Product Overview
Israpafant | T27638 | TargetMol Chemicals
CAS: 117279-73-9
Smiles: CC(C)Cc1ccc(CCc2cc3c(s2)-n2c(C)nnc2C(C)N=C3c2ccccc2Cl)cc1
Formula: C28H29ClN4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Israpafant is a selective antagonist for the platelet-activating factor receptor ( IC50 = 0.84nM). Israpafant inhibits PAF-induced human platelet aggregation. Israpafant inhibits the activation of eosinophil cells and consequently delays the development of immune responses. Israpafant also has anti-nephrotoxic properties and to mobilize calcium transport.
Molecular Weight: 489, 08