Product Overview
ISRIB (trans-isomer) | T6183 | TargetMol Chemicals
CAS: 1597403-47-8
Smiles: Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)cc2)cc1
Formula: C22H24Cl2N2O4
Pathway: Apoptosis|||Autophagy
Target: Apoptosis|||PERK|||Autophagy
Receptor: N/A
Bioactivity: ISRIB (trans-isomer), the trans-isomer of ISRIB, is a effective and specific PERK inhibitor (IC50: 5 nM).
Molecular Weight: 451, 34
