Product Overview
Istradefylline | T6552 | TargetMol Chemicals
CAS: 155270-99-8
Smiles: CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Formula: C20H24N4O4
Pathway: GPCR/G Protein|||Neuroscience
Target: Adenosine Receptor
Receptor: N/A
Bioactivity: Istradefylline(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Abuse, Sleep Disorder, Hepatic Impairment, Parkinson's Disease, and Restless Legs Syndrome, among others.
Molecular Weight: 384, 436
