Product Overview
IT-901 | T15601 | TargetMol Chemicals
CAS: 1584121-99-2
Smiles: COc1cc(OC)c2ccccc2c1C=C1C(=O)NC(=S)NC1=O
Formula: C17H14N2O4S
Pathway: NF-Κb
Target: NF-κB
Receptor: N/A
Bioactivity: IT-901 is an orally active and effective inhibitor of NF-κB subunit c-Rel (IC50s: 0.1 μM, 3 μM for NF-κB DNA binding and c-Rel DNA binding, respectively). IT-901 has the potential for human lymphoid tumors, and ameliorate graft-versus-host disease.
Molecular Weight: 342, 37
