Product Overview
Ivacaftor | T2588 | TargetMol Chemicals
CAS: 873054-44-5
Smiles: CC(C)(C)c1cc(c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)C(C)(C)C
Formula: C24H28N2O3
Pathway: Autophagy|||Membrane transporter/Ion channel
Target: CFTR|||Autophagy
Receptor: N/A
Bioactivity: Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.
Molecular Weight: 392, 499
