Product Overview
IWP-O1 | T5342 | TargetMol Chemicals
CAS: 2074607-48-8
Smiles: O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1
Formula: C26H20N6O
Pathway: Cytoskeletal Signaling|||Stem Cells
Target: Wnt/beta-catenin|||Porcupine
Receptor: N/A
Bioactivity: IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
Molecular Weight: 432, 487