Product Overview
J14 | T8320 | TargetMol Chemicals
CAS: 1043854-13-2
Smiles: OC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1
Formula: C28H25ClN4O2S
Pathway: Immunology/Inflammation|||Metabolism|||NF-Κb
Target: Reactive Oxygen Species
Receptor: N/A
Bioactivity: J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
Molecular Weight: 517, 04