Product Overview
JAK3i | T27650 | TargetMol Chemicals
CAS: 1918238-72-8
Smiles: CCOC(=O)c1c[nH]c2ncnc(-c3cc(NC(=O)C=C)ccc3F)c12
Formula: C18H15FN4O3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation.
Molecular Weight: 354, 341