Product Overview
JANEX-1 | T2045 | TargetMol Chemicals
CAS: 202475-60-3
Smiles: COc1cc2ncnc(Nc3ccc(O)cc3)c2cc1OC
Formula: C16H15N3O3
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells
Target: JAK
Receptor: N/A
Bioactivity: Janex-1 is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases.
Molecular Weight: 297, 314
