Product Overview
Jatrophane 2 | TN2727 | TargetMol Chemicals
CAS: 210108-86-4
Smiles: C[C@H]1\C=C\C(C)(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@H](OC(C)=O)C2[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]2(O)[C@H]1OC(C)=O)OC(C)=O
Formula: C39H50O15
Pathway: Membrane transporter/Ion channel|||Microbiology/Virology|||Neuroscience
Target: P-gp|||Antifection
Receptor: N/A
Bioactivity: 2, 5, 7, 8, 9, 14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17), 11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera). Jatrophane 2 also demonstrates the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR).
Molecular Weight: 758, 8
