Product Overview
JCN037 | T8431 | TargetMol Chemicals
CAS: 2305154-31-6
Smiles: Fc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12
Formula: C16H11BrFN3O2
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR
Receptor: N/A
Bioactivity: JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM, respectively).
Molecular Weight: 376, 185