Product Overview
JHU37152 | T9019 | TargetMol Chemicals
CAS: 2369979-67-7
Smiles: CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2cccc(F)c12
Formula: C19H20ClFN4
Pathway: Neuroscience
Target: AChR
Receptor: N/A
Bioactivity: JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
Molecular Weight: 358, 85