JHU37160 | T9018

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ā‚¬219.00 - ā‚¬1,183.00
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TMC-T9018
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Product Overview

JHU37160 | T9018 | TargetMol Chemicals

CAS: 2369979-68-8

Smiles: CCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2c(F)cccc12

Formula: C19H20ClFN4

Pathway: Neuroscience

Target: AChR

Receptor: N/A

Bioactivity: JHU 37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.

Molecular Weight: 358, 85

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