Product Overview
JNJ-31020028 | T1997 | TargetMol Chemicals
CAS: 1094873-14-9
Smiles: CCN(CC)C(=O)C(N1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2cccnc2)cc1F)c1ccccc1
Formula: C34H36FN5O2
Pathway: GPCR/G Protein|||Neuroscience
Target: Neuropeptide Y Receptor
Receptor: N/A
Bioactivity: JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
Molecular Weight: 565, 693
