Product Overview
JNJ-38158471 | T22349 | TargetMol Chemicals
CAS: 951151-97-6
Smiles: CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl
Formula: C15H17ClN6O3
Pathway: Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||c-RET|||c-Kit
Receptor: N/A
Bioactivity: CS-2660, a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM.
Molecular Weight: 364, 79
