Product Overview
JNJ-5207787 | T15620 | TargetMol Chemicals
CAS: 683746-68-1
Smiles: CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1cccc(c1)C#N
Formula: C32H38N4O2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 receptor and rat Y2 receptor, respectively.
Molecular Weight: 510, 682