Product Overview
JNJ-55511118 | T25558 | TargetMol Chemicals
CAS: 2036081-86-2
Smiles: FC(F)(F)Oc1cccc(Cl)c1-c1ccc2[nH]c(=O)[nH]c2c1
Formula: C14H8ClF3N2O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: JNJ-55511118 is a selective negative modulator of AMPA receptors containing TARP-γ8 (Ki: 26 nM). It had excellent pharmacokinetic properties. JNJ-55511118 exhibited a dose-dependent inhibition of neurotransmission within the hippocampus and a strong anticonvulsant effect.
Molecular Weight: 328, 68
