Product Overview
JNK-IN-8 | T2668 | TargetMol Chemicals
CAS: 1410880-22-6
Smiles: CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)c(C)c1
Formula: C29H29N7O2
Pathway: MAPK|||Tyrosine Kinase/Adaptors
Target: JNK|||c-Kit
Receptor: N/A
Bioactivity: JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRĪ² in A375 cell line.
Molecular Weight: 507, 598
