Product Overview
JTV-803 mesylate | T27698 | TargetMol Chemicals
CAS: 247131-79-9
Smiles: CS(O)(=O)=O.NC(=N)N1CCc2ccc(OCC3(CCN(CC3)c3ccncc3)C(O)=O)cc2C1
Formula: C23H31N5O6S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its inhibitory activity against thrombin, trypsin and plasmin. JTV-803 prolonged activated partial thromboplastin time and prothrombin time in a dose-dependent manner.
Molecular Weight: 505, 59
