Product Overview
JW 67 | T22884 | TargetMol Chemicals
CAS: 442644-28-2
Smiles: O=C1Nc2ccccc2C11OCC2(CO1)COC1(OC2)C(=O)Nc2ccccc12
Formula: C21H18N2O6
Pathway: Cytoskeletal Signaling|||Stem Cells
Target: Wnt/beta-catenin
Receptor: N/A
Bioactivity: JW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.
Molecular Weight: 394, 383
