JWG-071 | T14547

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TMC-T14547
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Product Overview

JWG-071 | T14547 | TargetMol Chemicals

CAS: 2250323-50-1

Smiles: CCC(C)N1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3OC)C(=O)N3CCC(CC3)N3CCN(C)CC3)nc12

Formula: C34H44N8O3

Pathway: MAPK

Target: ERK

Receptor: N/A

Bioactivity: JWG-071 is the first reported kinase-selective chemical probe for ERK5. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology[1]. JWG-071 improves ERK5 activity and BRD4 selectivity.

Molecular Weight: 612, 779

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