Product Overview
K-252c | T15638 | TargetMol Chemicals
CAS: 85753-43-1
Smiles: O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21
Formula: C20H13N3O
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling
Target: PKC
Receptor: N/A
Bioactivity: K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.
Molecular Weight: 311, 344
