Product Overview
KenPaullone | T2247 | TargetMol Chemicals
CAS: 142273-20-9
Smiles: Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1
Formula: C16H11BrN2O
Pathway: Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: GSK-3|||CDK
Receptor: N/A
Bioactivity: Kenpaullone, a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGFβ-Smad3 signaling pathway.
Molecular Weight: 327, 181
