Product Overview
KGA-2727 | T15656 | TargetMol Chemicals
CAS: 666842-36-0
Smiles: CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(OCCCNCCC(N)=O)cc1C
Formula: C26H40N4O8
Pathway: GPCR/G Protein
Target: SGLT
Receptor: N/A
Bioactivity: KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 for the treatment of diabete.
Molecular Weight: 536, 626
