Product Overview
Ki20227 | T4315 | TargetMol Chemicals
CAS: 623142-96-1
Smiles: COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1
Formula: C24H24N4O5S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: c-Fms|||VEGFR|||CSF-1R|||PDGFR|||c-Kit
Receptor: N/A
Bioactivity: Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR2(IC50: 12 nM) and c-Kit/PDGFRβ(IC50: 451/217 nM), respectively.
Molecular Weight: 480, 54
