Product Overview
Kobophenol A | TN4394 | TargetMol Chemicals
CAS: 124027-58-3
Smiles: Oc1ccc(cc1)[C@H]1O[C@@H]([C@@H]([C@@H]1c1cc(O)cc(O)c1)c1cc(O)cc2O[C@@H]([C@H](c12)c1cc(O)cc2O[C@H]([C@@H](c12)c1cc(O)cc(O)c1)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1
Formula: C56H44O13
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Immunology/Inflammation|||MAPK|||NF-Κb|||Proteases/Proteasome
Target: MMP|||BCL|||p38 MAPK|||NF-κB|||ROS|||DNA/RNA Synthesis|||CDK|||JNK
Receptor: N/A
Bioactivity: Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-dependent manner, and the IC50 value is 115.8mM. Kobophenol A has protective effect against nitrosative/oxidative or mitochondrial damages resulted in the inhibition of the ROS, intracellular calcium ion level, and mitochondrial transmembrane potential changes on SH-SY5Y cells.
Molecular Weight: 925