Product Overview
KPT330, (E)- | T1844 | TargetMol Chemicals
CAS: 1421923-86-5
Smiles: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ncn(\C=C\C(=O)NNc2cnccn2)n1
Formula: C17H11F6N7O
Pathway: Membrane transporter/Ion channel|||Others
Target: Others|||CRM1
Receptor: N/A
Bioactivity: KPT330, (E)- is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
Molecular Weight: 443, 313
