Product Overview
Kuwanon E | TN1848 | TargetMol Chemicals
CAS: 68401-05-8
Smiles: CC(C)=CCC\C(C)=C\Cc1cc([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)c(O)cc1O
Formula: C25H28O6
Pathway: Neuroscience
Target: AChR
Receptor: N/A
Bioactivity: Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively. Kuwanon E also inhibited the production of MUC5AC mucin induced by PMA from NCI-H292 cells, .
Molecular Weight: 424, 493