Product Overview
KY19382 | T9025 | TargetMol Chemicals
CAS: 2226664-93-1
Smiles: CO\N=C1/C(=Nc2ccccc12)c1c(O)[nH]c2cc(Cl)c(Cl)cc12
Formula: C17H11Cl2N3O2
Pathway: Cytoskeletal Signaling|||Others|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: Others|||GSK-3|||Wnt/beta-catenin
Receptor: N/A
Bioactivity: KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
Molecular Weight: 360, 19