KY19382 | T9025

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€240.00 - €3,426.00
SKU:
TMC-T9025
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Product Overview

KY19382 | T9025 | TargetMol Chemicals

CAS: 2226664-93-1

Smiles: CO\N=C1/C(=Nc2ccccc12)c1c(O)[nH]c2cc(Cl)c(Cl)cc12

Formula: C17H11Cl2N3O2

Pathway: Cytoskeletal Signaling|||Others|||PI3K/Akt/mTOR signaling|||Stem Cells

Target: Others|||GSK-3|||Wnt/beta-catenin

Receptor: N/A

Bioactivity: KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.

Molecular Weight: 360, 19

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