Product Overview
KYL acetate(676657-00-4 free base) | TP1895L1 | TargetMol Chemicals
CAS: TP1895L1
Smiles:
Formula: C76H112N14O19
Pathway: Tyrosine Kinase/Adaptors
Target: Ephrin Receptor
Receptor: N/A
Bioactivity: EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
Molecular Weight: 1525, 78
