L-873724 | T16092

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TMC-T16092
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Product Overview

L-873724 | T16092 | TargetMol Chemicals

CAS: 603139-12-4

Smiles: CC(C)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F)C(=O)NCC#N

Formula: C23H26F3N3O3S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: L-873724 inhibits bone resorption. L-873724 is an effective, selective, and reversible non-basic cathepsin K inhibitor (IC50s: 0.2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively). L-873724 also shows an IC50 of 0.5 nM for rabbit cathepsin K.

Molecular Weight: 481, 53

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